Immunology

Posted from Discovering Biology in a Digital World by Todd Smith on Fri May 03, 2019

Immunoproteosome

In early April 2019, the Institute for Systems Biology (ISB, Settle WA) hosted its 18th annual symposium. This year's theme focused on translational biology, which is the practice of commercializing research discovery. Over the two-day symposium, the audience was informed about the latest in the research and development of new products for fighting cancer with immunotherapy and combating research to ... Read more

Posted from Discovering Biology in a Digital World by Todd Smith on Wed Jan 23, 2019

Growth of NAR BioDBs
NAR databases since 1996. 2019 values are highlighted in red. NAR Database List

I always look forward to the Nucleic Acids Research (NAR) database issue . It's a great way to learn what people are interested in and learn something new. Its also fun to count the number of databases, because each way they're counted, a ... Read more

Posted from Discovering Biology in a Digital World by Todd Smith on Wed Dec 05, 2018

Immunoprofiling sample preparation

As previously discussed , immunoprofiling is the quantitative measurement of antigen receptors (ARs; antibodies or T-cell receptors) in a sample. Massively parallel (NextGen) DNA sequencing is a commonly used method for this purpose because receptor diversity can be quickly and cost-effectively measured with the added benefit that individual receptors can be quantified.

AR diversity is a ... Read more

Posted from Discovering Biology in a Digital World by Todd Smith on Wed Nov 07, 2018

Immunoprofiling steps of the general workflow
Growth of publications[1]. Key points in technology and company development are indicated.

Immunoprofiling, the quantitative measurement of antigen receptors (ARs; antibodies or T-cell receptors) in a sample, is a hot topic in biotechnology. In basic research, immunoprofiling is used to assess the diversity of antigen receptors (ARs: antibodies and T-Cell receptors) and how this diversity changes in ... Read more

Posted from Discovering Biology in a Digital World by Todd Smith on Tue Jul 10, 2018

Infographic: BCRs vs TCRs

Scientists, and science editors love acronyms. While they can be obfuscating, they help reduce cumbersome language.

For many years the term antibody was commonly abbreviated as Ab (Ig and others too). As high-throughput DNA sequencing has become a standard way to measure antibody and T cell receptor profiles it has also become common to compare these ... Read more

Posted from Discovering Biology in a Digital World by Todd Smith on Wed May 30, 2018

Immuno-Bioinformatics Infographic
Overview of the Immuno-Bioinformatics Course

In recent posts, I discussed container technology with an emphasis on Docker and Singularity . The motivation being that Digital World Biology is designing an immuno-bioinformatics class that will be taught at Shoreline Community College (Shoreline). This class will be part of Shoreline’s immuno-biotechnology certificate [1] that is currently under ... Read more

Posted from Discovering Biology in a Digital World by Todd Smith on Tue Jan 30, 2018

MHC-I with antigen from Molecule World

Lately I’ve been thinking about immunology, and not just because it is flu season, it is because Digital World Biology (DWB) is collaborating with Shoreline Community College to design a five-week bioinformatics course that will be component of their one year immuno-biotechnology certificate (1).

An aspect of the course will cover the ways in which industry studies and utilizes ... Read more