Precision BioSciences


The backbone of the ARCUS technology is the ARC Nuclease – a fully synthetic enzyme that is very similar to a homing endonuclease but is modified to be a better starting point for the development of new gene editing reagents. ARC Nuclease shares many of the positive attributes of a homing endonuclease, such as small size and unparalleled sequence specificity, but it can more easily be evolved into a custom gene editing tool that recognizes a DNA sequence of our choosing. Each ARCUS reagent is optimized using a set of proprietary in silico and lab-based techniques to ensure maximum gene editing efficiency with minimum off-target activity.

Durham NC
United States